منابع مشابه
Renal hypertrophy in experimental diabetes.
The effect of short-term diabetes, 5 days after the administration of streptozotocin, on renal growth and the activity of alternative pathways of glucose metabolism was studied in immature (21-day-old) rats and in adult rats. The kidney weight increased by 28% in the adult diabetic rats, but by only 10% in the immature diabetic rats, relative to their age-matched control groups. The flux of glu...
متن کاملEnsete superbum ameliorates renal dysfunction in experimental diabetes mellitus
Objective(s):Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. Materials and Methods:Glucose, HbA1c, total protein, albumin, renal function mar...
متن کاملensete superbum ameliorates renal dysfunction in experimental diabetes mellitus
objective(s):hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. in the present study, we evaluated the effect of ethanolic extract of ensete superbum seeds (esse) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. materials and methods:glucose, hba1c, total protein, albumin, renal function mark...
متن کاملTuberin in renal cell hypertrophy
Renal hypertrophy is an important prognostic indicator of progression of renal disease. Tubular cells, in particular those of the proximal tubule, are primary targets of hyperglycemia. Chronic exposure of renal cells to high glucose resulted in elevation of blood glucose and contributed to the tubulointerstitial. In diabetes, the renal tubule is subject to both direct and indirect insults. Rena...
متن کاملRenal sodium handling in experimental diabetes: role of NO.
Recent studies have suggested that diabetes is a state of increased renal nitric oxide (NO) activity as assessed by urinary excretion of nitrites and nitrates (NOx), and that NO synthase inhibitors reverse the increased glomerular filtration rate (GFR) observed in experimental diabetes. In addition to being a potent vasodilator in the renal vasculature, NO also plays a role in modulation of ren...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1980
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00261707